Tadalafil 20mg: Unveiling the Key Features
Gui í a de Salud Masculina
tadalafil (tadalafil) 20mg is a drug used to treat erectile dysfunction (ED) and pulmonary hypertension in men. Here are the details:
I. treatment of erectile dysfunction
1 、Mechanism of action
Tadalafil is a phosphodiesterase 5 (PDE5) inhibitor. During sexual stimulation, neurons in the penile cavernous body release nitric oxide (NO). NO activates guanosine cyclase and increases the level of cyclic guanosine monophosphate (cGMP), resulting in relaxation of smooth muscle in the corpus cavernosum of the penis, blood flow into the cavernous body of the penis, causing erection, and PDE5 degrades cGMP. Tadafil increases the concentration of cGMP by inhibiting PDE5. Helps to maintain penile erectile function.
2 、Usage
-when taken on demand, take it about 30 minutes to 12 hours before sexual activity. It should be noted that tadalafil does not cause libido and is effective only under sexual stimulation.
-you can also take low doses regularly as recommended by your doctor to improve erectile function.
3 、Matters needing attention
Cardiovascular healthIf the patient has severe cardiovascular disease, such as unstable angina pectoris, recent myocardial infarction, etc., it should be carefully evaluated before using tadalafil, because it will increase the cardiovascular burden during sexual activity. Tadalafil may further affect the cardiovascular system.
Interaction with other drugsTadalafil should not be used in conjunction with organic nitrates (such as nitroglycerin), as both may cause severe hypotension, and drug interactions may occur with some antihypertensive drugs, antifungal drugs, etc. inform your doctor of all drugs you are taking before use.
Second, the treatment of pulmonary hypertension
1 、Mechanism of action
In patients with pulmonary hypertension, tadalafil increases the level of cGMP in pulmonary vascular smooth muscle cells by inhibiting PDE5, thus relaxing pulmonary vessels, reducing pulmonary artery pressure, reducing right ventricular afterload and improving cardiopulmonary function.
2 、Usage
-it is usually taken regularly once a day, and the specific dose may need to be adjusted according to the patient's condition, age, weight and other factors.
3 、Matters needing attention
Regular monitoringPatients need to have regular heart function, lung function and other related tests to evaluate the efficacy and safety of the drug.
Adverse reaction managementThere may be headaches, blushing, indigestion and other adverse reactions, you should inform the doctor in time in order to adjust the treatment plan.