What is Tadalafilo? Unveiling the Mystery

El tadalafilo es un fármaco.

1. Medicinal properties and mechanism of action

Phosphodiesterase - 5 (PDE - 5) inhibitor:

- Tadalafil works by inhibiting the enzyme phosphodiesterase - 5. In the body, this enzyme breaks down cyclic guanosine monophosphate (cGMP). By inhibiting PDE - 5, tadalafil increases the levels of cGMP in the smooth muscle cells of the blood vessels in the penis (in men) or in the genital area (in both men and women).

- In men, this leads to relaxation of the smooth muscles in the corpus cavernosum of the penis, allowing increased blood flow into the penis during sexual stimulation, which helps in achieving and maintaining an erection.

2. Medical uses

Treatment of erectile dysfunction (ED) in men:

- It is one of the commonly prescribed medications for men who have difficulty in getting or maintaining an erection.

Treatment of pulmonary arterial hypertension (PAH):

- In patients with PAH, tadalafil helps to relax the pulmonary artery smooth muscle, dilate the pulmonary arteries, and reduce the pressure in the pulmonary circulation. This can improve exercise capacity and symptoms in patients with PAH.

3. Dosage and administration

- For erectile dysfunction, the typical starting dose is 10 mg, which can be adjusted depending on the individual's response and tolerability. It is usually taken as needed, but there are also lower - dose daily regimens available.

- For pulmonary arterial hypertension, the dosing regimen is different and is usually taken on a regular daily basis as prescribed by a healthcare provider.

4. Side effects

- Common side effects may include headache, indigestion, back pain, muscle aches, flushing, and nasal congestion. In rare cases, it may cause more serious side effects such as vision changes or priapism (a prolonged and painful erection in men).

It is important that tadalafil is used under the supervision of a healthcare professional, as they can assess the patient's suitability for the drug, monitor for side effects, and provide appropriate advice on its use.