What is Tadalafila 20 mg used for?

tadalafil 20 mg is used primarily for the following purposes:

1. Treatment of erectile dysfunction (ED)

Mechanism for action:

-Tadalafil inhibits the enzyme phosphodiesterase type 5 (PDE-5). This enzyme is responsible for degrading nitrogen monoxide (no)-cyclic monophosphate guanosin dependent (cGMP) in the vascular smooth muscle of the penis. By inhibiting PDE-5, tadalafil increases cGMP levels, resulting in smooth muscle relaxation in the blood vessels of the penis. This allows greater blood flow to the penis, facilitating erection.

Effectiveness:

-in clinical studies, tadalafil has been shown to be effective in improving the ability to achieve and maintain an erection sufficient for sexual penetration in a significant proportion of men with ED.

2. Treatment of pulmonary arterial hypertension (HTAP)

Mechanism for action:

-in HTAP, tadalafil works by relaxing the smooth muscles of the pulmonary blood vessels. By increasing cGMP levels, it reduces pulmonary blood pressure by dilating pulmonary vessels and improving blood flow in the lungs.

Effectiveness:

-has been shown to help improve functional capacity, quality of life and survival in patients with HTAP in combination with other standard treatments.

3. Treatment of erectile dysfunction and benign symptoms of prostatic hyperplasia (BPH)

Mechanism of action in BPH:

-although the exact mechanism is not fully understood, it is believed that by relaxing smooth muscles in the prostate and bladder, tadalafil can improve symptoms associated with BPH, such as difficulty urinating, urinary frequency, urinary urgency, and weak urinary flow.

Combined benefit:

-offers the advantage of simultaneously treating SD and BPH symptoms in men who have both problems.

However, tadalafil should be prescribed and used under medical supervision, as it may have interactions with other medications and may not be suitable for all people, especially those with certain heart conditions, low blood pressure, or who are taking nitrates.